Calendario
| Fecha | Fecha pronóstico | Local | Visitante | Resultado | Regla de puntos |
|---|---|---|---|---|---|
| 21/01/22 20:30 | 21/01/22 20:30 | Eintracht Frankfurt | Arminia Bielefeld | 0:2 | 2 - 7 - 8 |
| 22/01/22 15:30 | 22/01/22 15:30 | Bor. Mönchengladbach | 1. FC Union Berlin | 1:2 | 3 - 4 - 4 |
| 22/01/22 15:30 | 22/01/22 15:30 | Bayer Leverkusen | FC Augsburg | 5:1 | 2 - 8 - 8 |
| 22/01/22 15:30 | 22/01/22 15:30 | 1899 Hoffenheim | Borussia Dortmund | 2:3 | 6 - 5 - 3 |
| 22/01/22 15:30 | 22/01/22 15:30 | SC Freiburg | VfB Stuttgart | 2:0 | 2 - 7 - 8 |
| 22/01/22 15:30 | 22/01/22 15:30 | SpVgg Greuther Fürth | FSV Mainz 05 | 2:1 | 7 - 6 - 2 |
| 22/01/22 18:30 | 22/01/22 18:30 | VfL Bochum | 1. FC Köln | 2:2 | 5 - 3 - 3 |
| 23/01/22 15:30 | 23/01/22 15:30 | RB Leipzig | VfL Wolfsburg | 2:0 | 2 - 8 - 8 |
| 23/01/22 17:30 | 23/01/22 17:30 | Hertha BSC | FC Bayern de Múnich | 1:4 | 8 - 8 - 2 |