Calendario
| Fecha | Fecha pronóstico | Local | Visitante | Resultado | Regla de puntos |
|---|---|---|---|---|---|
| 27/08/21 20:30 | 27/08/21 20:30 | Borussia Dortmund | 1899 Hoffenheim | 3:2 | 3 - 9 - 9 |
| 28/08/21 15:30 | 28/08/21 15:30 | FC Augsburg | Bayer Leverkusen | 1:4 | 9 - 9 - 3 |
| 28/08/21 15:30 | 28/08/21 15:30 | FSV Mainz 05 | SpVgg Greuther Fürth | 3:0 | 3 - 9 - 9 |
| 28/08/21 15:30 | 28/08/21 15:30 | VfB Stuttgart | SC Freiburg | 2:3 | 4 - 5 - 6 |
| 28/08/21 15:30 | 28/08/21 15:30 | 1. FC Köln | VfL Bochum | 2:1 | 3 - 5 - 9 |
| 28/08/21 15:30 | 28/08/21 15:30 | Arminia Bielefeld | Eintracht Frankfurt | 1:1 | 9 - 7 - 3 |
| 28/08/21 18:30 | 28/08/21 18:30 | FC Bayern de Múnich | Hertha BSC | 5:0 | 3 - 9 - 9 |
| 29/08/21 15:30 | 29/08/21 15:30 | 1. FC Union Berlin | Bor. Mönchengladbach | 2:1 | 5 - 5 - 4 |
| 29/08/21 17:30 | 29/08/21 17:30 | VfL Wolfsburg | RB Leipzig | 1:0 | 7 - 7 - 4 |