| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 28/11/24 18:45 | Lazio Roma | PFC Ludogorets Razgrad | -:- |
| 28/11/24 18:45 | Dinamo de Kiev | Viktoria Pilsen | -:- |
| 28/11/24 18:45 | Qarabag | Olympique Lyon | -:- |
| 28/11/24 18:45 | Besiktas JK | Maccabi Tel Aviv | -:- |
| 28/11/24 18:45 | Rigas Futbola Skola | PAOK Salónica | -:- |
| 28/11/24 18:45 | RSC Anderlecht | FC Porto | -:- |
| 28/11/24 18:45 | Athletic Club | IF Elfsborg Boras | -:- |
| 28/11/24 18:45 | AZ Alkmaar | Galatasaray Estanbul | -:- |
| 28/11/24 21:00 | Slavia Praga | Fenerbahçe SK | -:- |
| 28/11/24 21:00 | Manchester United | FK Bodö/Glimt | -:- |
| 28/11/24 21:00 | Tottenham | AS Roma | -:- |
| 28/11/24 21:00 | Ferencvaros Budapest | Malmö FF | -:- |
| 28/11/24 21:00 | Sporting Braga | 1899 Hoffenheim | -:- |
| 28/11/24 21:00 | Real Sociedad de Fútbol | Ajax Amsterdam | -:- |
| 28/11/24 21:00 | FC Midtjylland | Eintracht Frankfurt | -:- |
| 28/11/24 21:00 | FCSB Bukarest | Olympiacos Piräus | -:- |
| 28/11/24 21:00 | OGC Niza | Glasgow Rangers | -:- |
| 28/11/24 21:00 | FC Twente Enschede | Royale Union Saint-Gilloise | -:- |