| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 23/10/24 16:30 | Sporting Braga | FK Bodö/Glimt | 1:2 |
| 23/10/24 16:30 | Galatasaray Estanbul | IF Elfsborg Boras | 4:3 |
| 24/10/24 18:45 | AS Roma | Dinamo de Kiev | 1:0 |
| 24/10/24 18:45 | Eintracht Frankfurt | Rigas Futbola Skola | 1:0 |
| 24/10/24 18:45 | Maccabi Tel Aviv | Real Sociedad de Fútbol | 1:2 |
| 24/10/24 18:45 | Ferencvaros Budapest | OGC Niza | 1:0 |
| 24/10/24 18:45 | PAOK Salónica | Viktoria Pilsen | 2:2 |
| 24/10/24 18:45 | FC Midtjylland | Royale Union Saint-Gilloise | 1:0 |
| 24/10/24 18:45 | Qarabag | Ajax Amsterdam | 0:3 |
| 24/10/24 21:00 | Fenerbahçe SK | Manchester United | 1:1 |
| 24/10/24 21:00 | Glasgow Rangers | FCSB Bukarest | 4:0 |
| 24/10/24 21:00 | FC Porto | 1899 Hoffenheim | 2:0 |
| 24/10/24 21:00 | Tottenham | AZ Alkmaar | 1:0 |
| 24/10/24 21:00 | Olympique Lyon | Besiktas JK | 0:1 |
| 24/10/24 21:00 | Malmö FF | Olympiacos Piräus | 0:1 |
| 24/10/24 21:00 | FC Twente Enschede | Lazio Roma | 0:2 |
| 24/10/24 21:00 | RSC Anderlecht | PFC Ludogorets Razgrad | 2:0 |
| 24/10/24 21:00 | Athletic Club | Slavia Praga | 1:0 |