| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 28/11/24 18:45 | Lazio Roma | PFC Ludogorets Razgrad | 0:0 |
| 28/11/24 18:45 | Dinamo de Kiev | Viktoria Pilsen | 1:2 |
| 28/11/24 18:45 | Qarabag | Olympique Lyon | 1:4 |
| 28/11/24 18:45 | Besiktas JK | Maccabi Tel Aviv | 1:3 |
| 28/11/24 18:45 | Rigas Futbola Skola | PAOK Salónica | 0:2 |
| 28/11/24 18:45 | RSC Anderlecht | FC Porto | 2:2 |
| 28/11/24 18:45 | Athletic Club | IF Elfsborg Boras | 3:0 |
| 28/11/24 18:45 | AZ Alkmaar | Galatasaray Estanbul | 1:1 |
| 28/11/24 21:00 | Slavia Praga | Fenerbahçe SK | 1:2 |
| 28/11/24 21:00 | Manchester United | FK Bodö/Glimt | 3:2 |
| 28/11/24 21:00 | Tottenham | AS Roma | 2:2 |
| 28/11/24 21:00 | Ferencvaros Budapest | Malmö FF | 4:1 |
| 28/11/24 21:00 | Sporting Braga | 1899 Hoffenheim | 3:0 |
| 28/11/24 21:00 | Real Sociedad de Fútbol | Ajax Amsterdam | 2:0 |
| 28/11/24 21:00 | FC Midtjylland | Eintracht Frankfurt | 1:2 |
| 28/11/24 21:00 | FCSB Bukarest | Olympiacos Piräus | 0:0 |
| 28/11/24 21:00 | OGC Niza | Glasgow Rangers | 1:4 |
| 28/11/24 21:00 | FC Twente Enschede | Royale Union Saint-Gilloise | 0:1 |