Calendario
| Fecha | Fecha pronóstico | Local | Visitante | Resultado | Regla de puntos |
|---|---|---|---|---|---|
| 12/11/21 2:20 | 12/11/21 2:20 | Miami Dolphins | Baltimore Ravens | 22:10 | 10 - 10 - 3 |
| 14/11/21 19:00 | 14/11/21 19:00 | New England Patriots | Cleveland Browns | 45:7 | 4 - 10 - 4 |
| 14/11/21 19:00 | 14/11/21 19:00 | Pittsburgh Steelers | Detroit Lions | 16:16OT | 3 - 10 - 10 |
| 14/11/21 19:00 | 14/11/21 19:00 | Indianapolis Colts | Jacksonville Jaguars | 23:17 | 3 - 10 - 10 |
| 14/11/21 19:00 | 14/11/21 19:00 | Tennessee Titans | New Orleans Saints | 23:21 | 4 - 10 - 5 |
| 14/11/21 19:00 | 14/11/21 19:00 | Dallas Cowboys | Atlanta Falcons | 43:3 | 3 - 10 - 10 |
| 14/11/21 19:00 | 14/11/21 19:00 | Washington Football Team | Tampa Bay Buccaneers | 29:19 | 10 - 10 - 3 |
| 14/11/21 19:00 | 14/11/21 19:00 | New York Jets | Buffalo Bills | 17:45 | 10 - 10 - 3 |
| 14/11/21 22:05 | 14/11/21 22:05 | Arizona Cardinals | Carolina Panthers | 10:34 | 3 - 10 - 10 |
| 14/11/21 22:05 | 14/11/21 22:05 | Los Angeles Chargers | Minnesota Vikings | 20:27 | 3 - 10 - 6 |
| 14/11/21 22:25 | 14/11/21 22:25 | Green Bay Packers | Seattle Seahawks | 17:0 | 3 - 10 - 5 |
| 14/11/21 22:25 | 14/11/21 22:25 | Denver Broncos | Philadelphia Eagles | 13:30 | 3 - 10 - 5 |
| 15/11/21 2:20 | 15/11/21 2:20 | Las Vegas Raiders | Kansas City Chiefs | 14:41 | 5 - 10 - 4 |
| 16/11/21 2:15 | 16/11/21 2:15 | San Francisco 49ers | Los Angeles Rams | 31:10 | 10 - 10 - 3 |