| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 16/03/23 18:45 | Real Betis Balompié | Manchester United | 0:1 |
| 16/03/23 18:45 | SC Freiburg | Juventus de Turin | 0:2 |
| 16/03/23 18:45 | Fenerbahçe SK | Sevilla F. C. | 1:0 |
| 16/03/23 18:45 | Feyenoord Rotterdam | Shaktar Donetsk | 7:1 |
| 16/03/23 21:00 | Arsenal FC | Sporting de Portugal | 4:6pen./1:190m |
| 16/03/23 21:00 | Ferencvaros Budapest | Bayer Leverkusen | 0:2 |
| 16/03/23 21:00 | Royale Union Saint-Gilloise | 1. FC Union Berlin | 3:0 |
| 16/03/23 21:00 | Real Sociedad de Fútbol | AS Roma | 0:0 |