| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 15/05/16 15:30 | SC Paderborn 07 | 1. FC Nürnberg | 0:1 |
| 15/05/16 15:30 | Eintracht Braunschweig | Fortuna Düsseldorf | 0:2 |
| 15/05/16 15:30 | FSV Frankfurt | TSV 1860 München | 2:1 |
| 15/05/16 15:30 | 1. FC Union Berlin | SC Freiburg | 2:1 |
| 15/05/16 15:30 | Karlsruher SC | Arminia Bielefeld | 1:1 |
| 15/05/16 15:30 | SpVgg Greuther Fürth | SV Sandhausen | 3:1 |
| 15/05/16 15:30 | MSV Duisburg | RB Leipzig | 1:0 |
| 15/05/16 15:30 | 1. FC Heidenheim 1846 | VfL Bochum | 2:4 |
| 15/05/16 15:30 | FC St. Pauli | 1. FC Kaiserslautern | 5:2 |