| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 22/10/22 19:00 | Union Santa Fe | Central Córdoba | 1:4 |
| 22/10/22 21:30 | Defensa y Justicia | Atletico Tucuman | 3:1 |
| 22/10/22 21:30 | CA San Lorenzo | CA Aldosivi | 3:0 |
| 22/10/22 21:30 | Estudiantes de La Plata | CD Godoy Cruz | 2:0 |
| 23/10/22 0:30 | Argentinos Juniors | CA Vélez Sarsfield | 2:0 |
| 23/10/22 17:00 | CA Banfield | CA Sarmiento Junin | 0:0 |
| 23/10/22 19:30 | CA Talleres | Gimnasia y Esgrima La Plata | 2:1 |
| 23/10/22 22:00 | CA Patronato Parana | CA Huracan | 3:2 |
| 23/10/22 22:00 | Racing Club | River Plate | 1:2 |
| 23/10/22 22:00 | Boca Juniors | Independiente | 2:2 |
| 24/10/22 20:30 | Barracas Central | Newell's Old Boys | 1:1 |
| 24/10/22 21:30 | Rosario Central | Club Atlético Colón | 1:1 |
| 25/10/22 1:30 | CA Tigre | Arsenal de Sarandi | 1:4 |
| 26/10/22 1:00 | CA Platense | CA Lanus | 1:1 |